MyBioSource.com's TRAIL-R2 (human) monoclonal antibody (DJR2-4) is a Mouse monoclonal antibody. The TRAIL-R2 (human) monoclonal antibody (DJR2-4) was generated using TNFRSF10B as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
DR5 is 55kDa member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon- alpha, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins